Medscape Headlines

Hypertension and Its Clinical Impact: A Report From the 2008 ACC

Tue, 13 May 2008 12:00:00 EDT

ACC '08: Dr. Jackson Wright reviews morbidity and mortality trials in hypertension and atherosclerosis; emerging data in diabetes therapy; and further insights into the risks with COX-2 inhibitors.
Medscape Cardiology

The Hemodynamics of Hypertension -- The Importance of Pathophysiology and Pharmacology

Tue, 13 May 2008 12:00:00 EDT

In this CME video lecture, Drs. Izzo and Giles explain the forces affecting hemodynamic patterns in hypertension and discuss potential therapeutic interventions to optimize flow.
Medscape Cardiology

Importance of Surgical Margins in the Management of Renal Cell Carcinoma

Tue, 13 May 2008 12:00:00 EDT

Partial nephrectomy is more commonly used for renal cell carcinoma, but there are concerns about complete tumor excision with this procedure. The current review examines the data in regard to this issue as well as best practices to improve the success of partial nephrectomy.
Nature Clinical Practice Urology

Molecular MRI of Hematopoietic Stem-progenitor Cells: In Vivo Monitoring of Gene Therapy and Atherosclerosis

Tue, 13 May 2008 12:00:00 EDT

Molecular MRI allows use of labeled hematopoietic stem-progenitor cells to identify diffuse atherosclerosis. New techniques in molecular MRI of atherosclerosis and their potential applications in clinical practice are reviewed.
Nature Clinical Practice Cardiovascular Medicine

Why the NIH Trial to Assess Chelation Therapy (TACT) Should Be Abandoned

Tue, 13 May 2008 08:53:01 EDT

The $30 million, NIH Phase 3 Trial to Assess Chelation Therapy (TACT) exposes subjects to a risky method that is known to be ineffective. The TACT should be abandoned and its origins investigated.
The Medscape Journal of Medicine

Early Screening of Women at High Risk for Gestational Diabetes Recommended

Tue, 13 May 2008 10:08:00 EDT

In many cases, gestational diabetes can be safely managed with oral agents instead of insulin.
Medscape Medical News

Gene Therapy Reduces Rate of Neurological Decline in Rare Lysosomal Storage Disease

Tue, 13 May 2008 10:26:46 EDT

Progression of late infantile neuronal ceroid lipofuscinosis slows in children who receive viral vectors expressing the normal form of the mutant gene.
Medscape Medical News

Disputed Echo Results From MIST I Require Regulatory Attention, Article States

Tue, 13 May 2008 14:00:12 EDT

Dr Jonathan Tobis argues that the FDA and the MHRA in the UK should step in to clear up the "mist of confusion" created by the disparate residual-shunt data reported officially and unofficially for MIST I. While the FDA is refusing to comment, the UK agency says it has reviewed the data and found no sign of safety or efficacy problems with the STARflex device.
Heartwire

Generic Clopidogrel Imminent, This Time in Europe

Tue, 13 May 2008 14:12:20 EDT

A generic version of clopidogrel is expected to be available soon in Germany and then other European countries, according to an announcement from Swiss pharmaceutical company Schweizerhall.
Heartwire

Moderate Doses of Vitamin D2 as Effective as D3 in Maintaining Serum 25-hydroxyvitamin D Levels

Tue, 13 May 2008 14:33:52 EDT

A daily dose of 1,000 IU vitamin D2 is as effective as 1,000 IU vitamin D3 in maintaining levels of serum 25-hydroxyvitamin D (25[OH]D), found this randomized, double-blind, placebo-controlled study.
NAMS

Million Women Study: Higher BMI Increases Cancer Incidence and Mortality

Tue, 13 May 2008 14:34:19 EDT

Higher body mass index (BMI) is significantly associated with an increased risk of incident and fatal cancers for 10 of 17 specific cancer types considered, and for all cancers combined.
The North American Menopause Society (NAMS)

Low-dose Vaginal Estradiol Tablets Relieve Symptoms of Vaginal Atrophy

Tue, 13 May 2008 14:35:43 EDT

Vaginal tablets with 25 μg and 10 μg estradiol both provide relief of symptoms of vaginal atrophy and improve urogenital health, found this multicenter, randomized, double-blind, parallel-group study.
NAMS

Liquid Pap No More Sensitive Than Conventional Pap in Cervical Cancer Screening and Prevention

Tue, 13 May 2008 14:37:59 EDT

Liquid-based cytology is not more sensitive nor more specific than a conventional Papanicolaou (Pap) smear for the detection of high-grade cervical intraepithelial neoplasia (CIN).
NAMS

NAMS Position Statement on Local Estrogen for Vaginal Atrophy

Tue, 13 May 2008 14:39:31 EDT

An evidence-based position statement published by The North American Menopause Society (NAMS) on the role of local vaginal estrogen therapy (ET) for the treatment of vaginal atrophy in postmenopausal
NAMS

What Is the Diagnosis of This ECG?

Tue, 13 May 2008 15:00:22 EDT

What clinical diagnosis can be made from this ECG tracing?
Medscape Cardiology

What Should I Do When I Suspect That a Patient Is Suicidal?

Tue, 13 May 2008 16:12:18 EDT

I work in a primary care setting. What is the best course of action if I suspect that a patient is suicidal?
Medscape Nurses

FDA Backpedals on Warnings in Echo-Contrast Labeling

Tue, 13 May 2008 16:14:00 EDT

Warnings and contraindications imposed late last year have been softened after the agency heard from the medical community.
Heartwire

Naproxen and Celecoxib Do Not Improve Cognitive Function in Elderly Patients

Tue, 13 May 2008 17:00:00 EDT

In the Alzheimer's Disease Anti-inflammatory Prevention Trial, use of naproxen or celecoxib did not improve cognitive function, and there was weak evidence for a detrimental effect of naproxen.
Medscape Medical News

Maternal Infections During Pregnancy May Increase Risk for Childhood Epilepsy

Tue, 13 May 2008 17:00:00 EDT

A study shows that young children exposed to various maternal infections, such as vaginal yeast infection and diarrhea, while in utero have an increased risk for epilepsy.
Medscape Medical News

Anticoagulant and Antiplatelet Therapy for Endoscopic Procedures Reviewed

Tue, 13 May 2008 17:00:00 EDT

Guidelines have been issued regarding proper anticoagulant and antiplatelet treatment of patients who undergo endoscopic procedures.
Medscape Medical News