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Tables for:
Infection in the Transplant Recipient

[Organ Transplant 2003. © 2003 Medscape]


Table 1. Treatment Regimens for HSV Infection in Transplant Recipients[29]


IndicationDrug and Dosage
Initial genital infectionAcyclovir 400 mg PO 5 times daily or valacyclovir 1 g PO 3 times daily, for 10 days
Recurrent genital infectionAcyclovir 400 mg PO 5 times daily or valacyclovir 1 g PO 2 times daily, for 5 days
Suppression of recurrent genital infectionAcyclovir 400 mg PO 2 or 3 times daily or valacyclovir 1 g PO once daily
Herpes labialisPenciclovir 1% topically every 2 h for 4 days or acyclovir 400 mg PO 5 times daily for 5 days
EncephalitisAcyclovir 10-15 mg/kg IV every 8 h for 14-21 days

Table 2. Treatment Regimens for Varicella Infection in Transplant Recipients[29]


IndicationDrug and Dosage
VaricellaAcyclovir 10 mg/kg IV every 8 h for 7-10 days
ZosterValacyclovir 1 g PO 3 times daily or acyclovir 800 mg PO 5 times daily for 7 days or acyclovir 10 mg/kg IV every 8 h for 7 days

Table 3. Treatment Regimens for CMV Infection in Transplant Recipients[29]


IndicationDrug and Dosage
ProphylaxisGanciclovir, 5 mg/kg IV 2 times daily, then 1 g 3 times daily to complete 3 months; valacyclovir 2 g PO 4 times daily for 3 months
TreatmentGanciclovir 5 mg/kg IV 2 times daily for 14 days, then 1 g 3 times daily to complete 6 weeks