Adverse Effect
Frequency (per million)
Postvaccination encephalopathy
1.9 to 12.3
Vaccinia necrosum
0.9 to 1.5
Eczema vaccinatum
8.7 to 38.5
Generalized vaccinia
20.8 to 241.5
Accidental autoinnoculation (74% involving eyes)
13.6 to 529.2
Deaths
0.8 to 1.1
Total adverse effects
52.9 to 823