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Tables for:
Adolescent Acne: A Stepwise Approach to Management

[Topics in Advanced Practice Nursing eJournal 2(2), 2002. © 2002 Medscape Portals, Inc]


Table 1. Patient Education: Basic Skin Care For Acne


Acne is a chronic condition, usually triggered by the onset of puberty and increasing hormone levels. It cannot be cured, but there are many things you can do to keep acne from becoming a major problem. Remember that all teens have acne to some extent, so you are not alone. Take control of your condition with good basic skin care using carefully selected products. Do not listen to every advertisement you hear, as some things might not be appropriate for you. Follow the instructions given by your healthcare provider. Try to be patient. Acne improvement takes time and attention.
Acne Myths
Myth 1: Vigorous cleansing with abrasive cleansers or sponges will remove blackheads and prevent acne. False. This causes microscopic tears in the skin and increases sites where Propionibacterium acnes (acne-causing bacteria) can enter the skin.
Myth 2: Eliminating certain foods from your diet will control acne. False. Foods do not worsen acne; however, a balanced diet helps the immune system work to maintain resistance to the bacteria that contribute to acne.
Myth 3: Squeezing pimples will clear them more quickly. False. Squeezing or touching pimples disrupts the follicular wall and causes redness and swelling of the surrounding skin, thus increasing the severity of acne and potential for scarring.
Dos and Don'ts of Skin Care
Do wash with mild, unscented soap. Twice daily cleansing is plenty. More frequent washing will only irritate the skin.
Don't use abrasive sponges or cloths. They cause irritation and allow bacteria to grow.
Do protect your skin from the sun. Use a sunscreen with SPF 15 daily, and wear a broad-brimmed hat for shade.
Don't use astringents and after-shaves that contain alcohol.
Do be faithful to daily skin care. The medication won't work if it stays in the bottle!


Table 2. Over-the-Counter Acne Products[10]


MedicationBrand NamesStrengthsVehiclesComments
Benzoyl peroxidePersagel,
Desquam-E
Oxy Wash, Fostex
2.5%, 5%, 10%Gel, wash, cream, lotionInitially irritating. Contact allergy in 2% of users. Start with 5% strength.
Lactic acid Clean & Clear,
Fostex, Aveeno,
Neutrogena

Liquid soap, bar soap, lotions
RetinolNeutrogena Multivitamin Acne Treatment, Neutrogena Skin Clearing Moisturizer Variable, not controlled by US Food and Drug Administration
Effectiveness not documented.
Salicylic acidOxy Wash, PropaPh, NeutrogenaAcne Wash1%, 2%, 5%Lotion, cream, wash, gel May irritate initially. Some are available with tint for cover-up.


Table 3. Topical Prescription Comedolytics[16]


MedicationBrand NameStrengthsVehicles and Dispensing SizeComments
AdapaleneDifferin0.1%Cream -- 15 g, 45 g
Gel -- 15 g, 45 g
Solution -- 30 cc
Wipes -- 60/box
Photosensitizing. Less irritating than tretinoin.
Azelaic acidAzelex20%Cream -- 30 g, 50 gNot photosensitizing. Synergistic when used with tretinoin.
TretinoinRetin-A Avita0.025%, 0.05%, 0.1%Cream -- 20 g, 45 g
Gel -- 15 g, 45 g
Lotion -- 28 cc
Photosensitizing. Initiate treatment at the lowest strength. Gels are stronger than cream, due to increased absorption.
Tazarotene Tazorac0.05%, 0.1% Cream -- 15 g, 30 g, 60 g
Gel -- 30 g, 100 g
No advantage over other products.
Combination Products
Benzoyl peroxide and erythromycinBenzamycinBP 5%, erythromycin 3%GelMust be refrigerated. Often irritating.
Benzoyl peroxide and clindamycinBenzaClinBP 5%, clindamycin 1%Alcohol-free, water based gelSometimes irritating. Contraindicated in those having a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis.


Table 4. Topical Antibiotics[16]


MedicationBrand NamesVehicles and Dispensing SizeComments
ErythromycinEryDerm, ATS, Emgel, ErycetteSolution -- 60 cc
Gel -- 27 g, 50 g
Wipes -- 60/box
66% alcohol
77% alcohol
66% alcohol
ClindamycinCleocinSolution -- 30 cc, 60 cc
Gel -- 30 g, 60 g
Lotion -- 60 cc
Wipes -- 60/box
50% alcohol
50% alcohol
5% alcohol
50% alcohol
Gentamycin 1% GaramycinCream -- 15 g
Ointment -- 15 g
Rarely used. Petrolatum base of ointment may help in acne excoriée
Metronidazole MetroGel 0.75%, MetroCream 0.75%

Noritate 1%
MetroLotion 0.75%

Gel -- 28 g
Cream -- 45 g
Cream -- 30 g
Lotion -- 60 cc
No alcohol but still irritating.
No alcohol.
No alcohol.
Sodium sulfacetamide 10%, sulfur 5%Sulfacet R, Novacet, KlaronLotion -- 25gNot for use by patients with kidney disease.


Table 5. Oral Antibiotics[16]


MedicationStrengthsStarting DoseMaintenance DoseComments
Tetracycline250 mg
500 mg
500 mg twice a day 250-500 mg dailyCalcium decreases absorption. Photosensitizing.
Doxycycline50 mg
100 mg
100 mg twice a day50-100 mg dailyCalcium decreases absorption. Photosensitizing. Erosive esophagitis.
Minocycline50 mg
100 mg
100 mg twice a day50-100 mg dailyMore expensive. More side effects including a potential to cause blue discoloration of teeth and skin.
Erythromycin250 mg
500 mg
500 mg twice a day500 mg dailySustained release less irritating to gastrointestinal tract.
Amoxicillin250 mg
500 mg
500 mg twice a day500 mg dailyUseful if erythromycin not tolerated.
Cephalexin500 mg500 mg twice a day500 mg dailyRarely used.