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  • Registry Data Support NOACs for Single-Risk-Factor AF Ischemic strokes rates were similar between atrial fibrillation patients treated with novel oral anticoagulants and warfarin, but imbalances in the study groups have raised questions.
  • Canakinumab Cuts Secondary CV Events in Phase 3 CANTOS Top-line results show the monoclonal antibody, given on top of standard care, significantly reduced the risk of cardiovascular death, nonfatal MI, and nonfatal stroke in patients with a prior MI and elevated CRP.
  • EHRA OAC Can Continue, With Cautions, During CIED Lead Extractions No heparin bridging needed, says a study from one experienced center. Bleeding complications at lead extractions were so rare that any oral anticoagulation could be maintained. Prospective trials are lacking.
  • EHRA Stopping NOACs for AF Ablation Caused Brain Lesions by MRI It's not considered unsafe anymore, but perhaps it should be entirely avoided. Routine cerebral imaging in a prospective series often showed new, asymptomatic lesions after interrupted oral anticoagulation.
 

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  • The War Over MOC Heats Up In at least 17 states, doctors are battling the American Board of Medical Specialties, hospitals, and insurers in an effort to make maintenance of certification optional. Here's how it's going.
  • A Hospital Gets Sued for Keeping a Patient Alive   Hospital clinicians who don't follow a patient's advance healthcare directive are at risk of being sued.

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  • ACOG Guidance: Individualize Breast Cancer ScreeningDecisions on when to start and end screening and on screening frequency should be made jointly by patients and providers, given the wide variation in major guidelines, ACOG said.
  • One Nut Allergy Doesn't Rule All Nuts OutContrary to past thinking, it isn't always necessary for someone with a nut allergy to dodge all nuts and seeds, and avoidance might even prompt more allergies, researchers warn.
  • Lying Flat vs Sitting Up: No Difference in Stroke OutcomesThe HeadPoST study -- showing no difference in disability outcomes in stroke patients who were laid flat vs those sitting up for the first 24 hours -- has now been published in the New England Journal of Medicine.

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  • Eric J. Topol, MD Eric J. Topol, MD Director, Scripps Translational Science Institute; Chief Academic Officer, Scripps Health; Professor of Genomics, The Scripps Research Institute; Senior Consultant, Division of Cardiovascular Diseases, Scripps Clinic, La Jolla, California; Editor-in-Chief, Medscape